In an era where decentralized technologies challenge the very foundations of traditional financial policymaking, how can regulators effectively combat money laundering? This book delves into the complex relationship between anti-money laundering regulations and the disruptive innovation of crypto-assets and blockchain technology. Through a critical analysis of the current European regulatory framework, lately enriched by the introduction of the Market in Crypto-assets Regulation, this book proposes a novel approach to bridging the gap between old and new paradigms. Essential reading for policymakers, legal scholars, and anyone interested in the future of financial regulation in decentralized environments.